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Calcium Carboxymethyl Cellulose (CMC) is a cellulose derivative that is commonly used as a disintegrant in pharmaceutical formulations. It is produced by the chemical modification of cellulose, where carboxymethyl groups are introduced to enhance its solubility and functionality. CMC is known for its ability to swell and promote the breakdown of tablets and capsules in the digestive tract, facilitating the release of active ingredients.
| Chemical formula | C6H7CaO8 |
| Purity | Typically 95% or higher |
| Viscosity | Varies from low to high depending on grade |
| pH range | 6.0 to 8.0 in a 1% solution |
| Moisture content | Usually less than 10% |
When selecting Calcium Carboxymethyl Cellulose, consider the specific grade required for your application, as viscosity and purity can vary significantly. It's important to specify the desired properties, such as disintegration time and moisture content, when requesting a quote. Additionally, inquire about any relevant certifications or compliance with pharmacopoeial standards applicable to your industry.
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It is primarily used as a disintegrant in tablet and capsule formulations.
Yes, it is generally recognized as safe and is widely used in various formulations.
Yes, it is also used as a thickening agent and stabilizer in the food industry.
It should be stored in a cool, dry place away from moisture and direct sunlight.
It absorbs water and swells, facilitating the breakdown of tablets in the digestive system.
Grades vary based on viscosity and purity, suitable for different applications.