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Crizotinib is an active pharmaceutical ingredient (API) used primarily in the treatment of certain types of cancer, particularly non-small cell lung cancer (NSCLC) that is characterized by specific genetic mutations. It functions as a tyrosine kinase inhibitor, targeting the ALK (anaplastic lymphoma kinase) and ROS1 genes to inhibit tumor growth. Crizotinib is typically available in oral form as a capsule, allowing for convenient administration in outpatient settings.
| Chemical formula | C21H22Cl2N4O2 |
| Molecular weight | 450.34 g/mol |
| Purity | ≥ 98% |
| Solubility | Soluble in organic solvents; poorly soluble in water |
| Storage conditions | Store in a cool, dry place, protected from light |
When selecting Crizotinib, buyers should consider the required purity levels and the specific formulation needed for their applications. It is important to specify the desired quantity, as bulk orders may have different pricing structures. Additionally, inquire about any relevant certifications or compliance with regulatory standards to ensure the product meets safety and efficacy requirements.
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Crizotinib is primarily used to treat non-small cell lung cancer (NSCLC) with ALK or ROS1 mutations.
Crizotinib is usually administered orally in capsule form.
Common side effects may include nausea, diarrhea, and visual disturbances.
Crizotinib is mainly available as oral capsules.
Consider purity, quantity, and compliance with regulatory standards.
Yes, it may be used in combination with other cancer therapies, but consult a healthcare professional.