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Dicalcium phosphate is a calcium phosphate compound commonly used as a filler and binder in pharmaceutical formulations. It typically appears as a white powder and is produced through the reaction of calcium hydroxide and phosphoric acid. This excipient is valued for its ability to improve the flow properties of powders and enhance the compressibility of tablets and capsules.
| Chemical formula | CaHPO4·2H2O |
| Purity | Typically 98% or higher |
| Particle size | 100 to 200 microns |
| pH range | 6.0 to 8.0 |
| Moisture content | Less than 5% |
When selecting dicalcium phosphate, consider the intended application and required purity levels. Specify the desired particle size and moisture content based on your formulation needs. It is also important to inquire about certifications such as GMP compliance and any relevant pharmacopoeial standards. Quantities can vary widely, so be clear about your order size to receive accurate pricing.
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It is primarily used as a filler and binder in tablets and capsules.
Yes, it is generally recognized as safe when used in appropriate amounts.
Yes, it is commonly used as a mineral supplement in animal nutrition.
It should be stored in a cool, dry place away from moisture.
It is considered safe, but excessive intake may lead to gastrointestinal issues.
Dicalcium phosphate contains two calcium ions and one phosphate ion, while calcium phosphate can refer to a variety of calcium phosphate compounds.