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Microcrystalline cellulose (MCC) is a widely used excipient in the pharmaceutical industry, primarily serving as a filler and binder in tablet formulations. It is derived from cellulose, a natural polymer found in plant cell walls, and is processed to create a fine, white powder that is odorless and tasteless. MCC is valued for its ability to improve the mechanical properties of tablets, enhance disintegration, and provide a stable matrix for active pharmaceutical ingredients (APIs).
| Chemical formula | C6H10O5 |
| Particle size | 50 to 200 microns |
| Moisture content | Typically less than 5% |
| Density | 0.3 to 0.6 g/cm³ |
| pH range | 4.5 to 7.5 |
When selecting microcrystalline cellulose, consider the specific application requirements such as particle size, moisture content, and purity levels. It is essential to specify any necessary certifications, such as pharmaceutical grade or food grade, depending on the intended use. Buyers should also determine the quantity needed, as bulk orders may affect pricing and availability.
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It is primarily used as a filler and binder in tablet formulations.
Yes, it is generally recognized as safe (GRAS) for use in food and pharmaceuticals.
MCC improves tablet hardness, disintegration, and stability.
Yes, since it is derived from plant cellulose.
It should be kept in a cool, dry place, away from moisture and direct sunlight.
Typical particle sizes range from 50 to 200 microns.