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Polysorbate 20 is a non-ionic surfactant commonly used as an emulsifier and solubilizer in pharmaceutical formulations. It is derived from sorbitol and fatty acids, which allows it to effectively reduce surface tension and improve the mixing of oil and water-based ingredients. This makes it particularly useful in the formulation of creams, lotions, and other topical products.
| Chemical structure | Polyethylene glycol sorbitan monolaurate |
| Appearance | Clear to pale yellow liquid |
| HLB value | 16.7 |
| Solubility | Soluble in water and oils |
| Typical usage concentration | 0.5% to 5% |
When selecting Polysorbate 20, consider the specific application and required properties such as the desired HLB value for emulsification. It's important to specify the intended use, as this may influence the grade and purity required. Additionally, inquire about certifications such as GMP compliance and the availability of documentation for regulatory purposes.
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It is primarily used as an emulsifier and solubilizer in various formulations.
Yes, it is generally recognized as safe for use in pharmaceuticals and cosmetics.
Yes, it is also used as an emulsifier in food applications.
Typical usage concentrations range from 0.5% to 5%.
It is derived from sorbitol and fatty acids, but specific allergen information should be checked based on the source.
Look for GMP compliance and any relevant safety certifications.