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Corn starch is a carbohydrate extracted from the endosperm of corn kernels. It is commonly used as a disintegrant in pharmaceutical formulations, helping tablets and capsules to break down and dissolve in the digestive system. Corn starch is valued for its ability to absorb moisture and its role in enhancing the bioavailability of active pharmaceutical ingredients (APIs).
| Appearance | Fine white powder |
| Solubility | Insoluble in cold water, soluble in hot water |
| Moisture content | Typically less than 14% |
| pH range | 4.5 to 7.0 |
| Particle size | Typically 100 to 200 microns |
When selecting corn starch as a pharmaceutical excipient, consider the specific grade required for your formulation, as different grades may have varying properties such as viscosity and disintegration time. It's important to specify the desired moisture content, particle size, and any relevant certifications such as GMP compliance. Additionally, determine the quantity needed for your production scale to ensure cost-effectiveness.
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Corn starch is primarily used as a disintegrant in tablet and capsule formulations.
Yes, corn starch is generally recognized as safe and is widely used in pharmaceutical applications.
Yes, corn starch is gluten-free and can be used in gluten-free products.
The typical moisture content for corn starch is less than 14%.
Corn starch can enhance the bioavailability of drugs by aiding in their disintegration and dissolution.
Corn starch should be stored in a cool, dry place to prevent moisture absorption.