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Palbociclib is a high-potency active pharmaceutical ingredient (API) used primarily in the treatment of certain types of breast cancer. It functions as a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), which play a crucial role in cell cycle regulation. By inhibiting these kinases, palbociclib helps to slow down or stop the proliferation of cancer cells. This compound is typically formulated into oral medications and is often used in combination with other therapies to enhance treatment efficacy.
| Chemical formula | C24H29N5O2 |
| Molecular weight | 445.52 g/mol |
| Purity | ≥ 98% (HPLC) |
| Solubility | Soluble in DMSO and ethanol |
| Storage conditions | Store at -20°C, protected from light |
When selecting palbociclib, buyers should consider the required purity levels and the specific formulation needed for their applications. It is essential to specify the desired quantity, as bulk orders may be necessary for manufacturing purposes. Additionally, inquire about any relevant certifications or compliance with regulatory standards, especially if the API will be used in clinical settings.
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Palbociclib is primarily used in the treatment of hormone receptor-positive breast cancer.
It is typically administered orally in capsule form.
Palbociclib should be stored at -20°C, away from light.
The typical purity is ≥ 98% as determined by HPLC.
Yes, it is often used in combination with other cancer treatments.
Safety data should be reviewed, including potential side effects and contraindications.