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Methotrexate is a potent anti-cancer medication that belongs to the class of drugs known as antimetabolites. It works by inhibiting the metabolism of folic acid, which is essential for the synthesis of nucleic acids, thereby disrupting the growth of rapidly dividing cancer cells. Methotrexate is typically available in both oral and injectable forms and is used in various treatment regimens for different types of cancers as well as autoimmune diseases.
| Chemical formula | C20H22N8O5 |
| Molecular weight | 454.44 g/mol |
| Solubility | Soluble in water and alcohol |
| Form | Powder or solution |
| Purity | Typically ≥ 99% |
When selecting methotrexate as a pharmaceutical raw material, buyers should consider the required purity levels and the specific formulation needed for their applications. It is important to specify the intended use, whether for cancer treatment or other therapeutic purposes, as well as any necessary certifications such as Good Manufacturing Practice (GMP). Additionally, buyers should indicate the desired quantity and delivery timelines when requesting quotes.
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Methotrexate is commonly used to treat leukemia, lymphoma, and certain solid tumors.
Yes, it is also used to treat autoimmune diseases like rheumatoid arthritis and psoriasis.
Methotrexate is available in oral tablets and injectable solutions.
It should be stored in a cool, dry place away from light.
Common side effects include nausea, fatigue, and increased risk of infection.
Yes, methotrexate can be prescribed for children, especially for certain cancers.