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Polysorbate 80, also known as Tween 80, is a non-ionic surfactant and emulsifier commonly used in pharmaceutical formulations, particularly in vaccines. It is derived from sorbitol and fatty acids, and functions by stabilizing emulsions and enhancing the solubility of hydrophobic compounds. In vaccine formulations, Polysorbate 80 helps to improve the distribution of active ingredients and maintain the stability of the final product.
| Purity | Typically greater than 99% |
| Appearance | Pale yellow to yellow liquid |
| Solubility | Soluble in water and many organic solvents |
| pH range | 5.0 to 7.0 |
| Molecular weight | Approximately 1,310 g/mol |
When selecting Polysorbate 80 for vaccine production, buyers should consider the required purity level and any specific regulatory certifications needed for pharmaceutical applications. It is important to specify the desired quantity and any specific packaging requirements. Additionally, buyers may want to inquire about the product's stability data and compatibility with other ingredients in their formulation.
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It acts as an emulsifier and stabilizer, improving the solubility and distribution of active ingredients.
Yes, it is widely used in pharmaceutical formulations and has been deemed safe for use in vaccines.
Yes, it is also used in various biopharmaceuticals, cosmetics, and food products.
It is typically greater than 99% purity.
It should be stored in a cool, dry place away from direct sunlight.
Polysorbate 80 is generally considered non-allergenic, but individual sensitivities may vary.