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Simvastatin is a medication used to lower cholesterol levels in the blood, primarily for the treatment of hyperlipidemia and the prevention of cardiovascular disease. It belongs to a class of drugs known as statins, which work by inhibiting the enzyme HMG-CoA reductase, a key player in the cholesterol synthesis pathway in the liver. This action helps to reduce levels of low-density lipoprotein (LDL) cholesterol and triglycerides while increasing high-density lipoprotein (HDL) cholesterol.
| Chemical formula | C25H38O5 |
| Molecular weight | 418.57 g/mol |
| Purity | Typically ≥ 98% |
| Form | Powder or crystalline |
| Solubility | Soluble in organic solvents, slightly soluble in water |
When selecting simvastatin as an active pharmaceutical ingredient, buyers should consider the required purity levels, as well as the form in which the API is needed (powder or crystalline). It is also important to specify any necessary certifications, such as Good Manufacturing Practice (GMP) compliance, and to discuss the desired quantities for production. Understanding the target market and regulatory requirements for the final product can also influence the choice of supplier.
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Simvastatin is primarily used to lower cholesterol levels and reduce the risk of cardiovascular diseases.
It works by inhibiting the enzyme HMG-CoA reductase, reducing cholesterol production in the liver.
Simvastatin is typically available as a powder or crystalline form.
Purity levels are typically ≥ 98%.
Simvastatin is slightly soluble in water but soluble in organic solvents.
It is used in pharmaceutical manufacturing and research related to cardiovascular health.