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Filgrastim is a recombinant form of human granulocyte colony-stimulating factor (G-CSF), primarily used to stimulate the production of white blood cells in patients undergoing chemotherapy or those with certain blood disorders. It is produced using biotechnological methods, typically involving genetically modified bacteria that express the G-CSF protein. Filgrastim plays a crucial role in reducing the risk of infection in patients with neutropenia by enhancing the immune response.
| Molecular weight | approximately 18 kDa |
| Formulation | Sterile solution for injection |
| Storage conditions | Refrigerated at 2°C to 8°C |
| Administration route | Subcutaneous or intravenous |
| Shelf life | Typically 24 months from the date of manufacture |
When purchasing filgrastim, buyers should specify the required formulation, such as the concentration and volume of the product. It is also important to consider the storage and handling requirements to ensure product integrity. Additionally, inquire about the manufacturer's compliance with relevant regulatory standards and certifications to ensure quality and safety. Quantities may vary based on the intended use, so providing an estimated usage rate can help suppliers offer appropriate packaging options.
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Filgrastim is used to stimulate white blood cell production in patients with neutropenia, particularly after chemotherapy.
Filgrastim is typically administered via subcutaneous injection or intravenous infusion.
Filgrastim should be stored refrigerated at 2°C to 8°C and protected from light.
The shelf life is generally around 24 months from the date of manufacture.
Common side effects may include bone pain, fatigue, and mild fever.
Yes, filgrastim can be used in children, but dosages may differ based on age and weight.
The safety of filgrastim during pregnancy has not been fully established; consult a healthcare provider.
If a dose is missed, administer it as soon as remembered, unless it's close to the next scheduled dose.