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Ketoconazole is an antifungal medication that belongs to the class of azole antifungals. It works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their growth and reproduction. Ketoconazole is typically available in both oral and topical formulations, making it versatile for various treatment applications.
| Chemical formula | C26H28Cl2N4O4 |
| Molecular weight | 531.43 g/mol |
| Solubility | Soluble in alcohol and chloroform, slightly soluble in water |
| Formulation types | Tablets, creams, shampoos |
| Storage conditions | Store in a cool, dry place, away from light |
When selecting ketoconazole as an active pharmaceutical ingredient, buyers should consider the intended formulation type, such as tablets or topical applications. It's important to specify the required purity levels and any relevant certifications, such as GMP compliance. Additionally, buyers should indicate the desired quantities and any specific packaging requirements to ensure compliance with regulatory standards.
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Ketoconazole is primarily used to treat fungal infections, including athlete's foot, ringworm, and seborrheic dermatitis.
Topical formulations of ketoconazole are often available over-the-counter, while oral forms typically require a prescription.
Common side effects may include skin irritation, nausea, and headache. Serious side effects can occur, so medical advice is recommended.
Ketoconazole should be used during pregnancy only if clearly needed and prescribed by a healthcare provider.
Ketoconazole should be stored in a cool, dry place, away from light to maintain its efficacy.
Ketoconazole works by inhibiting the synthesis of ergosterol, disrupting the fungal cell membrane.